Warning: Strong fentanyl including medetomidine
Through anecdotal reports and observations with on site drug testing at Carepoint Consumption & Treatment Services, we would like to share the following information about possible side effects that could be associated with fentanyl potentially cut with medetomidine. Please note: Multiple colours of the substance currently associated with this advisory have been reported.
Some of the possible side effects include:
- An increase in "tranquilizer-like" reactions.
- Unusually difficult to rouse, sleep-like state but not in overdose as vital signs are stable (AKA "a heavy nod”).
- Significant confusion after waking up, including lost sense of time.
In the community, a person can present as not responding to stimulation after multiple doses of naloxone, but is breathing and has a pulse. They may appear to be in a deep sleep-like state. It is still important to call 911. Substances such as fentanyl can be 'cut' (or mixed) with other drugs. Even a very small amount can cause an overdose or other side effects.
Harm reduction recommendations when using substances:
- Try not to use alone.
- If you use alone, tell someone where you are. Ask them to check on you.
- Use in small doses.
- Avoid mixing substances, if possible.
- Encourage use of Carepoint (Mon-Sun: 9AM-9PM).
- Have naloxone ready and know how to respond to an overdose
For more information, please contact Director of Harm Reduction Services, Megan Van Boheemen, at mvanboheemen@hivaidsconnection.ca or 226.377.8721.
Posted September 2, 2025. Please remove this notice by September 13, 2025 as the unregulated drug supply changes constantly.